Search results for "Systematic survey"

showing 5 items of 5 documents

A Systematic Study of Dysregulated MicroRNA in Type 2 Diabetes Mellitus

2017

MicroRNAs (miRNAs) are small noncoding RNAs that modulate the cellular transcriptome at the post-transcriptional level. miRNA plays important roles in different disease manifestation, including type 2 diabetes mellitus (T2DM). Many studies have characterized the changes of miRNAs in T2DM, a complex systematic disease; however, few studies have integrated these findings and explored the functional effects of the dysregulated miRNAs identified. To investigate the involvement of miRNAs in T2DM, we obtained and analyzed all relevant studies published prior to 18 October 2016 from various literature databases. From 59 independent studies that met the inclusion criteria, we identified 158 dysregu…

0301 basic medicineSystematic surveytype 2 diabetes mellitussystematic study030209 endocrinology & metabolismDiseaseBioinformaticsCatalysisArticleInorganic ChemistryTranscriptomelcsh:Chemistry03 medical and health sciences0302 clinical medicineDiabetes mellitusmiRNA-mRNA interaction networkmicroRNAmedicineHumansGene Regulatory NetworksRNA MessengerPhysical and Theoretical Chemistry10. No inequalityMolecular Biologylcsh:QH301-705.5SpectroscopyAdipocytokine Signaling PathwaymicroRNA; type 2 diabetes mellitus; miRNA-mRNA interaction network; systematic studymicroRNAbusiness.industryGene Expression ProfilingOrganic ChemistryType 2 Diabetes MellitusGeneral Medicinemedicine.diseaseComputer Science ApplicationsMicroRNAs030104 developmental biologyDiabetes Mellitus Type 2Gene Expression Regulationlcsh:Biology (General)lcsh:QD1-999Organ SpecificityRNA InterferenceDisease manifestationbusinessTranscriptomeSignal TransductionInternational Journal of Molecular Sciences
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An integrated program of geophysical survey, coring, and test excavations to study a 4th millennium bc-cal ditch at Alt del Punxó (Muro de L’alcoi, A…

2008

The potentially long and interesting archaeological sequence revealed by systematic survey at the site of Alt Del Punxó (Muro de l’Alcoi, Alacant) was the basis for initiating a study of the locality’s subsurface structures using new methods of remote sensing. Geophysical survey (magnetometry and tomography) and systematic augering revealed buried structures, including monumental earthworks, and guided subsequent excavations to collect more detailed data about the nature and age of these prehistoric features. The information recovered, including new radiocarbon dates, offers a new perspective on the organization of prehistoric populations in this region of south-central Valencia since the b…

ArcheologySystematic surveyPenínsula IbéricaMagnetometríalaw.inventionPrehistorylawC14Radiocarbon datinglcsh:CC1-960NeolithicHoloceneGeophysical SurveyMagnetrometryExcavationRemote sensingMonumental EarthworksSystematic surveyArchaeologyElectrical TomographyGeographyProspectionRemote sensing (archaeology)Geophysical survey (archaeology)Prospección sistemáticaAugeringlcsh:ArchaeologyMicrosondeosEstructuras monumentalesTomografía eléctrica. Neolítico Final
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Traditional Chinese herbal medicine at the forefront battle against COVID-19: Clinical experience and scientific basis.

2020

Abstract Background Throughout the 5000-year history of China, more than 300 epidemics were recorded. Traditional Chinese herbal medicine (TCM) has been used effectively to combat each of these epidemics’ infections, and saved many lives. To date, there are hundreds of herbal TCM formulae developed for the purpose of prevention and treatment during epidemic infections. When COVID-19 ravaged the Wuhan district in China in early January 2020, without a deep understanding about the nature of COVID-19, patients admitted to the TCM Hospital in Wuhan were immediately treated with TCM and reported later with >90% efficacy. Approach We conducted conduct a systematic survey of various TCM herbal pre…

PTGS2 Prostaglandin-endoperoxide synthase 2BattleAIV avian influenza virusCoV coronavirusPharmaceutical ScienceiNOS nitric oxide synthaseViral infection0302 clinical medicinePA patchouli alcoholSARS Severe Acute Respiratory SyndromeSMD Sheganmahuang decoctionDrug DiscoveryPandemicIL InterleukinMedicine Chinese TraditionalALI acute lung injuriesmedia_commonCOVID-19 coronavirus disease 2019MXSG Ma xing shi gan decoction0303 health sciencesTNF tumor necrosis factorClinical Trials as TopicCCL2 CC chemokine ligand 2FM1 FM1 coronavirusICU intensive care unitc-AMP cyclic adenosine phosphateHIV human immunodeficiency virus030220 oncology & carcinogenesisCOX-2 cyclooxygenase-2Molecular MedicineHerbal preparationsMedicinal herbsAbbreviations: ACE2 angiotensin-converting enzyme IITCM traditional Chinese medicineHSV-1 herpes simplex virus 1CASP3 caspase 3medicine.medical_specialtyChinaCoronavirus disease 2019 (COVID-19)Systematic surveymedia_common.quotation_subjectJEV Japanese encephalitis virusNF-κB nuclear factor kappa B cellsAntiviral AgentsArticleWHO World Health Organization03 medical and health sciencesIEC-6 rat intestinal epithelial cell line 6SOD superoxide dismutaseCDC Center for Disease Control and PreventionmedicineAVP arginine vasopressinPGE2 prostaglandin E2HumansIntensive care medicineLH Lianhuaqingwen capsule030304 developmental biologyPharmacologyMedicinal herbMDA malondialdehydeGCGJ Gancao ganjiang decoctionNO nitric oxidePlants Medicinalbusiness.industrySARS-CoV-2COVID-19CXCL C-X-C- motif chemokineMDCK Madin-Darby Canine Kidney cellsTLR-4 Toll-like receptor-4COVID-19 Drug TreatmentComplementary and alternative medicineViral infectionLPS lipopolysaccharidesRSV respiratory syncytial virusQFPD Qingfeipaidu decoctionbusinessLung congestionECMO extracorporeal membrane oxygenationMAPK mitogen-activated protein kinasePhytotherapyDrugs Chinese HerbalPhytomedicine : international journal of phytotherapy and phytopharmacology
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Quality of reporting in abstracts of RCTs published in emergency medicine journals: a protocol for a systematic survey of the literature

2017

Introduction The quality of reporting of abstracts of randomised controlled trials (RCTs) in major general medical journals and in some category-specific journals was shown to be poor before the publication of the ConsolidatedStandards of ReportingTrials (CONSORT) extension for abstracts in 2008, and an improvement in the quality of reporting of abstracts was observed after its publication. The effect of the publication of the CONSORT extension for abstracts on the quality of reporting of RCTs in emergency medicine journals has not been studied. In this paper, we present the protocol of a systematic survey of the literature, aimed at assessing the quality of reporting in abstracts of RCTs p…

Research Reportmedicine.medical_specialtyResearch methodologySystematic surveymedia_common.quotation_subjectAlternative medicineAccident & emergency medicine03 medical and health sciences0302 clinical medicineQuality of reportingProtocolMedicineHumansQuality (business)030212 general & internal medicine1506Abstractmedia_commonRandomized Controlled Trials as TopicProtocol (science)Research ethicsImpact factorbusiness.industryPublicationsConsolidated Standards of Reporting Trials030208 emergency & critical care medicineGeneral Medicinehumanities1691Statistics &research methodsEmergency medicineEmergency MedicineMedline databasebusinessBMJ Open
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Integrated Geophysical Investigations at the Greek Kamarina Site (Southern Sicily, Italy)

2018

Kamarina, located in southern Sicily (Italy), was an important Greek colony since its foundation in the sixth century BC. Archaeological excavations, carried out since the twentieth century, uncovered only limited portions of the site so far. Despite the importance of the Greek colony, the presence of remarkable buildings that archaeologists expected to bring to light has not found fully correspondence in the archaeological excavations. Consequently, the integrated geophysical prospection carried out in the study area is aimed to support and address the future archaeological investigations. After the photographic and thermographic survey obtained by an unmanned aerial vehicle, we performed …

Systematic surveyGPRHigh resolution010502 geochemistry & geophysics01 natural sciencesKamarinaSixth centuryGeochemistry and PetrologySettore GEO/11 - Geofisica Applicata0601 history and archaeologyCluster analysiSicilyGeophysic0105 earth and related environmental sciences060102 archaeologyGeophysical prospectionFoundation (engineering)ExcavationGround magnetic survey06 humanities and the artsGeophysicsIntegrated approachArchaeogeophysicUAV thermographyGeophysicsGround-penetrating radarGeology
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